Listning ID 209748
LYSODREN Mitotane - LYSODREN Mitotane
Description / Instruction
Mitotan is an inhibitor of the function of the adrenal cortex: inhibits the secretion of corticosteroids (hormones of the adrenal cortex), may cause destructive changes (changes structure) of normal and tumor tissue of the adrenal cortex.
Used for inoperable tumors (cancer not amenable to surgical treatment) of the adrenal cortex (corticosterone), accompanied by increased formation of corticosteroids, as well as after surgical removal of corticosteron at an elevated level of glucocorticoids (hormones of the adrenal cortex that regulate carbohydrate and protein metabolism) in the body. Also used as a prophylactic agent after removal of corticosterone in the absence of visible metastases (new tumors appeared in other organs and tissues as a result of migration of cancer cells from blood or lymph from the primary tumor) and the continuing high level of glucocorticoids in the body. Also shown, if necessary, suppress the excessive secretion of glucocorticoids in Itsenko-Cushing (obesity accompanied by decreased sexual function, increased bone fragility due to the enhanced allocation of adrenocorticotropic hormone of the pituitary gland) in combination with surgery or without it.
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